Villainesses who make secret plans to do something illegal or harmful.
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- Abigail Williams (The Crucible)
- Aethyr (Smallville)
- Agent Kalashnikov (Robotboy)
- Alexis (Man from Interpol)
- Amber Freeman (Scream)
- Amy Hughes (Dead of Summer)
- Angela (The Man From U.N.C.L.E.)
- Angela Grant/The Fox (Lady Penelope)
- Ava Bennett (Knight Rider)
- Barbary Red (The Big Valley)
- Beryl (Storie Blu)
- Beth (Scream)
- Betty Boswell (Terror Blu)
- Bezzie Powell (La Schiava)
- Bombalurina (Cats)
- Bonnie Douglas (The Lone Wolf)
- Bonnie Parazzo (Crossing Jordan)
- Brigid O’Shaughnessy (The Maltese Falcon)
- Brooke Mathison (Designated Survivor)
- Carla Hastings (Cyclone)
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- Circe Bishop (The Avengers)
- Claire Wyden (Rampage)
- Claudia Torrell (Knight Rider)
- Cleopatra (Freaks)
- Conrade (Much Ado About Nothing 2012)
- Courtney Lane (Law & Order: SVU)
- Cynthia Fields and Edy Cornfield (Dante)
- Danica Harlan (Altered Carbon)
- Denise Daniels (Criminal Case)
- Elexis Sinclaire (SiN)
- Erica Chan (CSI: Cyber)
- Evelyn (Mr Lucky)
- Flavia Ducasse (Il Marchese)
- Ga'ran Sigatar Khura'in (Ace Attorney)
- Galina Casban (A Wheel of Time)
- Grand High Witch (The Witches)
- Guy Champion (The Swordsman)
- Hilda (Fire Emblem: Genealogy of the Holy War)
- Irma Vep (Les Vampires)
- Jacqueline de Bellefort (Death On The Nile 2022)
- Jasmine (Crackerjack 2)
- Jessica Delacourt (Elysium)
- Jill Roberts (Scream 4)
- Jimmy (The Mysteries of Laura)
- Joanna (The Commuter)
- Julie Ryan (Law & Order: SVU)
- Kelly Donovon (Hawaii Five-0)
- Kenny Case (Arrest and Trial)
- Lily Carver (Kiss Me Deadly)
- Lindo (Alien From The Darkness)
- Linka Karensky (The Wrecking Crew)
- Lucy Williams (Ripcord)
- Lulu, the "Countess" (Black Cat)
- Magda Mather (James Bond)
- Maggie Lynch (Honey West)
- Margo Vicky (Kidnap)
- Margo Yeager (Sand Trap)
- Medusa (The New Fantastic Four)
- Millicent Fairbush (Remington Steele)
- Minister Ferro (Diamantino)
- Miss Davies (The Champions)
- Miss Grey (Mr Lucky)
- Monica (68 Kill)
- Nicki (Blonde Phantom)
- Nina (Wonder Woman)
- Olivia Peterson (Wicked Moms Club)
- Pandora (Rambo: The Force Of Freedom)
- Poppy Adams (Kingsman: The Golden Circle)
- Queen Lara (Outlaw of Gor)
- Queen Nisaba (Rulah, Jungle Goddess)
- Queen Vassa (Aquaman)
- Raven Red (Jet Dream And Her Stunt Girl Counterspies)
- Rhea (Supergirl)
- Rose Armitage (Get Out)
- Ruby (The Family)
- Sally Marnes (Traffik)
- Samantha Lee (Dante)
- Silkie (Amos Burke: Secret Agent)
- Sonia and Natasha Matamouros (Diamantino)
- Ta-She (Thundercats)
- Taho (Rulah, Jungle Goddess)
- Tara (Rulah, Jungle Goddess)
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- Victoria (The Man from U.N.C.L.E.)
- Victoria Leeds (Baywatch)
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- White Flower (Sub-Mariner)
- Yuri (Girl From Nowhere)
- Zena Sylberg (Storie Blu)
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- Abbey Lake (Cold Case)
- Abigail Moss (The Wild Wild West)
- Abigail Spencer (CSI)
- Abigail, Amanda & Amy (Relic Hunter)
- Addie (Mama's Dirty Girls)
- Adele Manning (No Place to Hide)
- Adele Pinchelow (Dumb and Dumber To)
- Adina (Supernatural)
- Adnan Salif (Scandal)
- Adrea Spedding (The Spider Woman)
- Adria (Stargate SG-1)
- Adriana Gorgova (NCIS)
- Adrienna Brassiere (Criminal Case)
- Adulterous Murderer (You're Next)
- Agatha (Two Sentence Horror Stories)
- Agatha Cackle (The Worst Witch 2017)
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- Agent Fitzgerald (Unnatural History)
- Agent Jackson (Key and Peele)
- Agnes Throckmorton (Strange Fantasy)
- AJ (Castle)
- Aksana (WWE)
- Alana Gonzalez (Law & Order: SVU)
- Alchemy (Phantasm II)
- Alda Hertzog (FlashForward)
- Alex Wesker (Resident Evil: Revelations 2)
- Alexa Comescu (NCIS: Los Angeles)
- Alexa Cooper (Dead on Campus)
- Alexa Lee (Lucifer)
- Alexandra Bastegar (Armored Command)
- Alexandra Combs (Bones)
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- Alexandra Schwartz (NCIS: New Orleans)
- Ali Weiss (Lethal Weapon)
- Alice (Prik Gub Klur)
- Alice Flagg (Honeymoon From Hell)
- Alice Hart (Fear Street)
- Alice Hill (New Tricks)
- Alice Sands (Rizzoli & Isles)
- Alice Vanderbilt (Rizzoli & Isles)
- Alicia Gramble (Crossing Jordan)
- Alicia Hunt (Batman)
- Alicia Minault (An Aurora Teagarden Mystery)
- Alicia Phelps (The Inspectors)
- Alika (Flashman)
- Alisa Silvermane (Spider-Man: The Animated Series)
- Alison Peters (Tales From the Crypt)
- Allie Banks (Twin Betrayal)
- Allison Clark (Monk)
- Allison Cowley (Psych)
- Allison Grady (CSI: Miami)
- Allison Hyde (Castle)
- Allison Scott (CSI: NY)
- Ally Moore (The Closer)
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- Alvida (One Piece)
- Amadea Denaris (The Finder)
- Amanda Debs (Murder, She Wrote)
- Amanda Harris (Blue Bloods)
- Amanda Haynes (CSI)
- Amanda Tanner (Scandal)
- Amanda Temple (Unforgettable)
- Amanda Vale (The Wild Wild West)
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- Amber (Dan Vs.)
- Amber (MacGyver)
- Amber Middleberry (Castle)
- Ambrosia (Dark Matter)
- Amelia Chase (Law & Order: SVU)
- Amira Dudayev (24: Legacy)
- Amy (68 Kill)
- Amy (Whiskey Cavalier)
- Amy Barrett (Castle)
- Amy Cohen (Republic of Doyle)
- Amy Dunne (Gone Girl)
- Amy Morgan (Castle)
- Ana Miller (Tomb Raider)
- Andrea (Beyond Belief: Fact or Fiction)
- Andrea Barnes (Ransom)
- Andrea Brown (Stalker)
- Andrea Dean (Murder, She Wrote)
- Andrea Fleming (Framed For Murder: A Fixer Upper Mystery)
- Andrea Glassen (Windows)
- Andrea Johnson (Tales From the Crypt)
- Andrea Kent (Law & Order: SVU)
- Andrea Rivers (Diagnosis Murder)
- Angela Alvarez (Careful What You Wish For)
- Angela Goodwin (NCIS: New Orleans)
- Angela Gordon (Abbott and Costello Meet the Killer, Boris Karloff)
- Angela Martin (Body of Proof)
- Angela Moss (Mr. Robot)
- Angela Muir (Who Killed My Husband?)
- Angela Olvera (Castle)
- Angelica Dira (The Finder)
- Angelica Wingate (Kamillions)
- Angelina Jennings (NCIS)
- Angelina Love (TNA)
- Angelique (Hellraiser: Bloodline)
- Angie (Perception)
- Angie (Robocop 2)
- Angie Chavira (Hunter)
- Angie Green (Double Jeopardy)
- Angie McHenry (Stuber)
- Angie Reynolds (Quantico)
- Anika Hauten (Crossing Lines)
- Anita Karr (NCIS: New Orleans)
- Anita Roycewood (Criminal Minds)
- Ann Cameron (Get Smart)
- Ann Cleary (Blue Bloods)
- Ann Ostilow (Law & Order: SVU)