Desire was a vampiress who had been prowling the dark streets of various towns before arriving in Los Angeles, in the guise of a nurse named Mona. She worked at the same hospital as the main protagonist, David Balsiger, who worked as a coroner's assistant, and she came in physical contact with David at one point when she attacked him. After his encounter with the vampiress and learning more about her from an ex-communicated priest named Paul, David encountered Mona he was driving down the street, and he later drives Mona to her home.
Mona later invited David into her house, and it is at that moment that she starts to come on to him, right before she went upstairs to change. She slowly comes downstairs in a black gown and continues seducing David, who resists her villainous advances. Mona later cemented her heel turn and revealed herself as the vampiress, Desire, as she followed David upstairs. Shortly afterwards, the evil Desire continued to pursue David and managed to trap him on a balcony, but when she leapt towards him, she fell to her death.
- Barbara Stock also portrayed the villainous Scam Woman in an episode of the sitcom Seinfeld, and also appeared as the evil Grace Spencer on Charmed.