Jana Murphy was a former FBI agent who gave up her career to become a stay-at-home mother and raise her children with her lover, FBI Agent Gina Mendez. According to Gina, Jana developed post-partum depression after giving birth to her son, and in a psychotic rage, she murdered the neighbor's dog. In her first appearance in the episode, "Family Affair," Jana is revealed to be one of the twisted followers of serial killer Joe Carroll, and she was also revealed to have helped Joe fake his death in-between Seasons One and Two.
In the episode "Unmasked," Jana's connection to Joe Carroll is discovered by Gina, who learns that Jana used Gina's security clearance to continue to help Joe. Gina confronts Jana at their home, only to be stabbed and spat on by the psychotic villainess (Gina survived), who was planning to leave to further help Joe. Jana's plan is thwarted when Ryan and Mike stop her, only for Jana to pull a gun on both of them. When asked by Ryan regarding Joe's whereabouts, Jana instead placed her gun to her head and committed suicide with a single shot.
- Leslie Bibb also played the evil Cayla Shelby from CSI: Miami, working as part of a villainous trio. She also went on to play Aimee Brells from the YouTube Red series Rhett and Link's Buddy System.