Layla Simmons was originally reported missing without a trace, until protagonist Hank Helton discovered her at a nightclub. The club is revealed to be a haven for vampires, and Hank is shocked to discover that Layla is a vampire herself. Later in the film, the evil Layla encountered Hank once again, and attempted to seduce Hank, all the while displaying her vampire fangs and features. She and her male vampire accomplice, later went after Hank and his ex-wife, Susan Hastings, in a hotel room, but they were fought off. While searching for Susan (who was taken by the master vampire, Hank finds Layla in her resting place, and gets Susan's location out of her before killing her with a wooden stake.
- Jodi Lyn O'Keefe is arguably most famous for portraying bully Taylor Vaughan in the 1999 teen movie She's All That and Gretchen Morgan on Prison Break.
- Jodi Lyn O'Keefe's other villainous roles include serial killer Debbie Strand in Devil in the Flesh 2, murderous femme fatale Lisa from The Finder, the evil Spider Demon from Charmed, tragic alternate reality villainess Gina Wright in A Nanny's Revenge, evil stepmother Lucy Lafleur on Eve, Satan worshipper Isabella on Two and a Half Men, and bully Candace Aimes from Tru Calling.