Serena (Josie Davis) is a villainess from the TV series Chuck. She appears in the episode "Chuck Versus First Class"

She is one of two Ring agents transporting the key to the Ring Intelligence Safe on a flight from Los Angeles to Paris.

She was placed aboard the flight in the guise of a flight attendant to support Ring agent Hugo Panzer during his mission. Serena freed Panzer after he was disabled in the cargo hold, and poisoned Chuck to force him to return the key.

She was later incapacitated by falling luggage after Sarah took control of the aircraft via satellite and destabilized it, and was apprehended when the flight arrived in France. Shaw expressed a familiarity with Serena's tactics, and implicated her in several poisonings of high-ranking officials.